The prognostic value of plasma galectin-3 in chronic heart failure patients is maintained when treated with mineralocorticoid receptor antagonists.

The prognostic value of plasma galectin-3 in chronic heart failure patients is maintained when treated with mineralocorticoid receptor antagonists.

Galectin-3 (Gal-3) is considered as a myocardial fibrosis biomarker with prognostic value in heart failure (HF). Since aldosterone is a neurohormone with established fibrotic properties, we aimed to investigate if mineralocorticoid receptor antagonists (MRAs) would modulate the prognostic value of G...

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Main Authors: François Koukoui, Franck Desmoulin, Michel Galinier, Manon Barutaut, Celine Caubère, Maria Francesca Evaristi, Gurbuz Murat, Rudolf De Boer, Matthieu Berry, Fatima Smih, Philippe Rouet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364698?pdf=render

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http://europepmc.org/articles/PMC4364698?pdf=render

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