Upregulation of NPL4 promotes bladder cancer cell proliferation by inhibiting DXO destabilization of cyclin D1 mRNA

Abstract Background NPL4 is an important cofactor of the valosin-containing protein (VCP)–NPL4–UFD1 complex. The VCP–NPL4–UFD1 has been considered as a ubiquitin proteasome system (UPS) regulator and response to protein degradation. While NPL4 plays important roles in various diseases, little is kno...

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Bibliographic Details
Main Authors: Bao-Sai Lu, Yue-Wei Yin, Yan-Ping Zhang, Ping-Ying Guo, Wei Li, Kai-Long Liu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cancer Cell International
Subjects:
DXO
Online Access:http://link.springer.com/article/10.1186/s12935-019-0874-2