Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression.

Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression.

Identifying microRNA signatures for the different types and subtypes of cancer can result in improved detection, characterization and understanding of cancer and move us towards more personalized treatment strategies. However, using microRNA's differential expression (tumour versus normal) to d...

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Bibliographic Details
Main Authors: Aziz M Mezlini, Bo Wang, Amit Deshwar, Quaid Morris, Anna Goldenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788788?pdf=render

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http://europepmc.org/articles/PMC3788788?pdf=render

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