Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model

Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model

Deep brain stimulation (DBS) applied to the nucleus accumbens (NAc) alleviates the depressive symptoms of major depressive disorders. We investigated the mechanism of this effect by assessing gene expression and RNA methylation changes in the ventral tegmental area (VTA) following NAc-DBS in a chron...

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Bibliographic Details
Main Authors: Song Nan, Du Jun, Gao Yan, Yang Shenglian
Format: Article
Language:English
Published: De Gruyter 2020-11-01
Series:Translational Neuroscience
Subjects:
depression
deep brain stimulation
nucleus accumbens
chronic unpredictable mild stress
rna methylation
Online Access:https://doi.org/10.1515/tnsci-2020-0146

Internet

https://doi.org/10.1515/tnsci-2020-0146

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