Methodologies for the analysis of HCV-specific CD4+ T cells

Methodologies for the analysis of HCV-specific CD4+ T cells

Virus-specific CD4+ T cells play a major role in viral infections, such as hepatitis C virus (HCV). Viral clearance is associated with vigorous and multispecific CD4+ T cell responses, while chronic infection has been shown to be associated with weak or absent T cell responses. Most of these studies...

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Bibliographic Details
Main Authors: Megha eLokhande, Robert eThimme, paul eKlenerman, Nasser eSemmo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
Hepatitis C
CD4 T cells
Viral Hepatitis
FACS
Tetramers
Elispot
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00057/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00057/full

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