A mechanism for matrikine regulation in acute inflammatory lung injury

Proline-glycine-proline (PGP) and its acetylated form (Ac-PGP) are neutrophil chemoattractants generated by collagen degradation, and they have been shown to play a role in chronic inflammatory disease. However, the mechanism for matrikine regulation in acute inflammation has not been well establish...

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Bibliographic Details
Main Authors: Sarah W. Robison, JinDong Li, Liliana Viera, Jonathan P. Blackburn, Rakesh P. Patel, J. Edwin Blalock, Amit Gaggar, Xin Xu
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-04-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.140750