Animal models in osteosarcoma

Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to r...

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Bibliographic Details
Main Authors: Maria V eGuijarro, Steven C. Ghivizzani, C. Parker Gibbs
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Oncology
Subjects:
p53
RB
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00189/full