Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

The penetration of cariogenic oral bacteria into enamel and dentin during the caries process triggers an immune/inflammatory response in the underlying pulp tissue, the reduction of which is considered a prerequisite to dentinogenesis-based pulp regeneration. If the role of odontoblasts in dentin fo...

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Bibliographic Details
Main Authors: Jean-Christophe eFARGES, Aurélie eBellanger, Maxime eDucret, Elisabeth eAubert-Foucher, Beatrice eRichard, Brigitte eAlliot-licht, Françoise eBleicher, Florence eCarrouel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Physiology
Subjects:
Nitric Oxide
Streptococcus mutans
Toll-Like Receptor 2
Tooth
odontoblast
Antibacterial response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00185/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00185/full

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