Insulin enhances renal glucose excretion: relation to insulin sensitivity and sodium-glucose cotransport

Introduction Insulin regulates renal glucose production and utilization; both these fluxes are increased in type 2 diabetes (T2D). Whether insulin also controls urinary glucose excretion is not known.Methods We applied the pancreatic clamp technique in 12 healthy subjects and 13 T2D subjects. Each p...

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Bibliographic Details
Main Authors: Ele Ferrannini, Ricardo Pereira-Moreira, Marta Seghieri, Eleni Rebelos, Aglécio L Souza, Valeria B Chueire, Caterina Arvia, Elza Muscelli
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/1/e001178.full