Effect of probe characteristics on the subtractive hybridization efficiency of human genomic DNA

<p>Abstract</p> <p>Background</p> <p>The detection sensitivity of low abundance pathogenic species by polymerase chain reaction (PCR) can be significantly enhanced by removing host nucleic acids. This selective removal can be performed using a magnetic bead-based solid...

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Bibliographic Details
Main Authors: Lin Baochuan, Long Nina, Archer Marie J
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/3/109