The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces Chlamydia trachomatis Infectivity and Growth

Invasion of epithelial cells by the obligate intracellular bacterium Chlamydia trachomatis results in its enclosure inside a membrane-bound compartment termed an inclusion. The bacterium quickly begins manipulating interactions between host intracellular trafficking and the inclusion interface, dive...

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Bibliographic Details
Main Authors: Mathilde M. Cossé, Michael L. Barta, Derek J. Fisher, Lena K. Oesterlin, Béatrice Niragire, Stéphanie Perrinet, Gaël A. Millot, P. Scott Hefty, Agathe Subtil
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00145/full