In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma

In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma

Pardaxin (H-GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE-OH), a 33-amino-acid polypeptide, is an antimicrobial peptide (AMP) isolated from the marine fish species Pardachirus marmoratus. Pardaxin shows antibacterial and antitumor activities. However, pardaxin-induced inhibition of oral cancer and the mechanism...

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Bibliographic Details
Main Authors: Yifan Han, Zhibin Cui, Yen-Hsing Li, Wei-Hsuan Hsu, Bao-Hong Lee
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Marine Drugs
Subjects:
pardaxin
antimicrobial peptide (AMP)
oral squamous cell carcinoma (OSCC) cells
7,12-dimethylbenz[a]anthracene (DMBA)
oral cancer
Online Access:http://www.mdpi.com/1660-3397/14/1/2

Internet

http://www.mdpi.com/1660-3397/14/1/2

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