Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
Gastrointestinal (GI) dysfunction is the one of the most common non-motor symptoms of Parkinson's disease (PD) and occurs in nearly every patient afflicted with this common neurodegenerative disorder. While parkinsonian motor symptoms are caused by degeneration of dopamine neurons in the midbra...
Main Authors: | Ali Reza Noorian, Jennifer Rha, Dana M. Annerino, Douglas Bernhard, Georgia M. Taylor, James G. Greene |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112002136 |
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