Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system

Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system

Gastrointestinal (GI) dysfunction is the one of the most common non-motor symptoms of Parkinson's disease (PD) and occurs in nearly every patient afflicted with this common neurodegenerative disorder. While parkinsonian motor symptoms are caused by degeneration of dopamine neurons in the midbra...

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Bibliographic Details
Main Authors: Ali Reza Noorian, Jennifer Rha, Dana M. Annerino, Douglas Bernhard, Georgia M. Taylor, James G. Greene
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Synuclein
Gastrointestinal
Gastric emptying
Constipation
Vagus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002136

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http://www.sciencedirect.com/science/article/pii/S0969996112002136

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