Computational Modeling to Explain Why 5,5-Diarylpentadienamides are TRPV1 Antagonists
Several years ago, the crystallographic structures of the transient receptor potential vanilloid 1 (TRPV1) in the presence of agonists and antagonists were reported, providing structural information about its chemical activation and inactivation. TRPV1’s activation increases the transport of calcium...
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Format: | Article |
Language: | English |
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MDPI AG
2021-03-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/26/6/1765 |