Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection

The transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key master switch that controls the expression of antioxidant and cytoprotective enzymes, including enzymes catalyzing glutathione de novo synthesis. In this study, we aimed to analyze whether Nrf2 deficiency influences...

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Bibliographic Details
Main Authors: Ralf Erkens, Tatsiana Suvorava, Thomas R. Sutton, Bernadette O. Fernandez, Monika Mikus-Lelinska, Frederik Barbarino, Ulrich Flögel, Malte Kelm, Martin Feelisch, Miriam M. Cortese-Krott
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/8309698