Modelling HIV and MTB co-infection including combined treatment strategies.
A new host-pathogen model is described that simulates HIV-MTB co-infection and treatment, with the objective of testing treatment strategies. The model includes CD4+ and CD8+ T cells, resting and activated macrophages, HIV and Mycobacterium tuberculosis (MTB). For TB presentation at various stages o...
Main Authors: | Santosh Ramkissoon, Henry G Mwambi, Alan P Matthews |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3509125?pdf=render |
Similar Items
-
Bayesian modeling of spatiotemporal patterns of TB-HIV co-infection risk in Kenya
by: Verrah Otiende, et al.
Published: (2019-10-01) -
Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons
by: Katalin A. Wilkinson, et al.
Published: (2021-03-01) -
Modelling the interaction between human immunodeficiency virus, mycobacterium tuberculosis and the human immune system, including the effects of drug therapy.
by: Ramkissoon, Santosh.
Published: (2010) -
Immune Phenotype and Functionality of <i>Mtb-</i>Specific<i> </i>T-Cells in HIV/TB Co-Infected Patients on Antiretroviral Treatment
by: Lucy Mupfumi, et al.
Published: (2020-03-01) -
Elevated Levels of Galectin-9 but Not Osteopontin in HIV and Tuberculosis Infections Indicate Their Roles in Detecting MTB Infection in HIV Infected Individuals
by: Ashwini Shete, et al.
Published: (2020-07-01)