Modelling HIV and MTB co-infection including combined treatment strategies.

A new host-pathogen model is described that simulates HIV-MTB co-infection and treatment, with the objective of testing treatment strategies. The model includes CD4+ and CD8+ T cells, resting and activated macrophages, HIV and Mycobacterium tuberculosis (MTB). For TB presentation at various stages o...

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Bibliographic Details
Main Authors: Santosh Ramkissoon, Henry G Mwambi, Alan P Matthews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3509125?pdf=render