Extremely low frequency electromagnetic field in combination with β-Lapachone up-regulates the genes of non-homologous end joining

Background and purpose: Non-homologous end joining (NHEJ) is the major pathway for removing DNA double strand breaks lesions. NHEJ is considered to be a resistant factor against chemotherapy induced neuropathy. β-Lapachone (β-Lap) is one of the antineoplastic agents which is shown to have anti neuro...

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Bibliographic Details
Main Authors: Fatemeh Sanie-Jahromi, Hamideh Mahmoudinasab, Mostafa Saadat
Format: Article
Language:English
Published: SpringerOpen 2017-10-01
Series:Egyptian Journal of Medical Human Genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863017300460