Extremely low frequency electromagnetic field in combination with β-Lapachone up-regulates the genes of non-homologous end joining
Background and purpose: Non-homologous end joining (NHEJ) is the major pathway for removing DNA double strand breaks lesions. NHEJ is considered to be a resistant factor against chemotherapy induced neuropathy. β-Lapachone (β-Lap) is one of the antineoplastic agents which is shown to have anti neuro...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2017-10-01
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Series: | Egyptian Journal of Medical Human Genetics |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1110863017300460 |