Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH

Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH

Tools that allow acute and selective silencing of synaptic transmission in vivo would be invaluable for understanding the synaptic basis of specific behaviors. Here, we show that presynaptic expression of the proton pump archaerhodopsin enables robust, selective, and reversible optogenetic synaptic...

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Bibliographic Details
Main Authors: Mohamady El-Gaby, Yu Zhang, Konstantin Wolf, Christof J. Schwiening, Ole Paulsen, Olivia A. Shipton
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Subjects:
optogenetics
archaerhodopsin
pH
synaptic silencing
synapses
reversible
behavior
long-term memory
hippocampus
asymmetry
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309883

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http://www.sciencedirect.com/science/article/pii/S2211124716309883

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