Predicting Drug-Target Interactions via Within-Score and Between-Score

Network inference and local classification models have been shown to be useful in predicting newly potential drug-target interactions (DTIs) for assisting in drug discovery or drug repositioning. The idea is to represent drugs, targets, and their interactions as a bipartite network or an adjacent ma...

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Bibliographic Details
Main Authors: Jian-Yu Shi, Zun Liu, Hui Yu, Yong-Jun Li
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/350983