Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease

<p>Abstract</p> <p>Background</p> <p>Huntington's Disease (HD) is an inherited autosomal dominant genetic disorder in which neuronal tissue degenerates. The pathogenesis of the disease appears to center on the development of protein aggregates that arise initially...

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Bibliographic Details
Main Authors: Parekh-Olmedo Hetal, Yerkes Sarah, Roth Jennifer, Skogen Michael, Kmiec Eric
Format: Article
Language:English
Published: BMC 2006-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/7/65