Phase II study of the combination carboplatin <it>plus </it>celecoxib in heavily pre-treated recurrent ovarian cancer patients

<p>Abstract</p> <p>Background</p> <p>Cyclooxygenase-2 overexpression is associated with poor outcome and resistance to platinum-based chemotherapy in ovarian cancer. We evaluated the antitumor activity and safety of the combination carboplatin plus the COX-2 inhibitor c...

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Bibliographic Details
Main Authors: Fuoco Gilda, D'Asta Marco, Paglia Amelia, Legge Francesco, Scambia Giovanni, Ferrandina Gabriella
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/214