Predictive potential of flux balance analysis of Saccharomyces cerevisiae using as optimization function combinations of cell compartmental objectives.

BACKGROUND: The main objective of flux balance analysis (FBA) is to obtain quantitative predictions of metabolic fluxes of an organism, and it is necessary to use an appropriate objective function to guarantee a good estimation of those fluxes. METHODOLOGY: In this study, the predictive performance...

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Bibliographic Details
Main Authors: Carlos Eduardo García Sánchez, César Augusto Vargas García, Rodrigo Gonzalo Torres Sáez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3415429?pdf=render