Mycobacterium smegmatis Bacteria Expressing Mycobacterium tuberculosis-Specific Rv1954A Induce Macrophage Activation and Modulate the Immune Response

Mycobacterium smegmatis Bacteria Expressing Mycobacterium tuberculosis-Specific Rv1954A Induce Macrophage Activation and Modulate the Immune Response

Mycobacterium tuberculosis (M. tb), the intracellular pathogen causing tuberculosis, has developed mechanisms that endow infectivity and allow it to modulate host immune response for its survival. Genomic and proteomic analyses of non-pathogenic and pathogenic mycobacteria showed presence of genes a...

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Bibliographic Details
Main Authors: Simran Kaur Arora, Nilofer Naqvi, Anwar Alam, Javeed Ahmad, Basma Saud Alsati, Javaid Ahmad Sheikh, Prabin Kumar, Dipendra Kumar Mitra, Syed Asad Rahman, Seyed Ehtesham Hasnain, Nasreen Zafar Ehtesham
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
host-pathogen interface
immune modulation
oxidative stress
signature protein
Th1 response
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.564565/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.564565/full

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