Adult mesenchymal stem cell ageing interplays with depressed mitochondrial Ndufs6

Abstract Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy to treat many degenerative diseases. Accumulating evidence shows that the function of MSCs declines with age, thus limiting their regenerative capacity. Nonetheless, the underlying mechanisms that control MSC ageing a...

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Bibliographic Details
Main Authors: Yuelin Zhang, Liyan Guo, Shuo Han, Ling Chen, Cheng Li, Zhao Zhang, Yimei Hong, Xiaoxian Zhang, Xiaoya Zhou, Dan Jiang, Xiaoting Liang, Jianxiang Qiu, Jinqiu Zhang, Xin Li, Shilong Zhong, Can Liao, Bin Yan, Hung-Fat Tse, Qizhou Lian
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03289-w