Melatonin Protects Against Ischemic Brain Injury by Modulating PI3K/AKT Signaling Pathway via Suppression of PTEN Activity

Melatonin Protects Against Ischemic Brain Injury by Modulating PI3K/AKT Signaling Pathway via Suppression of PTEN Activity

Stroke is one of the leading causes of death and disability worldwide with limited therapeutic options. Melatonin can attenuate ischemic brain damage with improved functional outcomes. However, the cellular mechanisms of melatonin-driven neuroprotection against post-stroke neuronal death remain unkn...

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Bibliographic Details
Main Authors: Yuanyuan Ran, Lin Ye, Zitong Ding, Fuhai Gao, Shuiqing Yang, Boyan Fang, Zongjian Liu, Jianing Xi
Format: Article
Language:English
Published: SAGE Publishing 2021-06-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/17590914211022888

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https://doi.org/10.1177/17590914211022888

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