Post-transcriptional and epigenetic regulation of antigen processing machinery (APM) components and HLA-I in cervical cancers from Uighur women.

Normal function of human leukocyte antigen class I (HLA-I) and antigen processing machinery (APM) proteins is required for T cell-mediated anti-tumor or antiviral immunity, whereas the tumor survival indicates a failure of the host in immune surveillance associated with the dysfunction in antigen pr...

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Bibliographic Details
Main Authors: Ayshamgul Hasim, Mangnishahan Abudula, Reshalaiti Aimiduo, Jun-Qi Ma, Zhen Jiao, Gulzareye Akula, Ting Wang, Abulizi Abudula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3443204?pdf=render