Embracing the dropouts in single-cell RNA-seq analysis

The analysis of RNA-seq data is complicated by dropouts, and these are usually treated as a problem to be addressed. Here, Peng Qiu uses dropouts as a source of information and presents a co-occurrence clustering algorithm to cluster cells based on the dropout pattern; this could be a complementary...

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Bibliographic Details
Main Author: Peng Qiu
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14976-9