Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE.

Translational models directly relating drug response specific processes that can be observed in vitro to their in vivo role in cancer patients constitute a crucial part of the development of personalized medication. Unfortunately, current studies often focus on the optimization of isolated model cha...

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Bibliographic Details
Main Authors: Lisa-Katrin Schätzle, Ali Hadizadeh Esfahani, Andreas Schuppert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007803