Acid sphingomyelinase serum activity predicts mortality in intensive care unit patients after systemic inflammation: a prospective cohort study.

Acid sphingomyelinase is involved in lipid signalling pathways and regulation of apoptosis by the generation of ceramide and plays an important role during the host response to infectious stimuli. It thus has the potential to be used as a novel diagnostic marker in the management of critically ill p...

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Bibliographic Details
Main Authors: Matthias Kott, Gunnar Elke, Maike Reinicke, Supandi Winoto-Morbach, Dirk Schädler, Günther Zick, Inéz Frerichs, Norbert Weiler, Stefan Schütze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4226549?pdf=render