Transcriptional and physiological roles for STAT proteins in leptin action

Transcriptional and physiological roles for STAT proteins in leptin action

Objectives: Leptin acts via its receptor LepRb on specialized neurons in the brain to modulate food intake, energy expenditure, and body weight. LepRb activates signal transducers and activators of transcription (STATs, including STAT1, STAT3, and STAT5) to control gene expression. Methods: Because...

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Bibliographic Details
Main Authors: Warren Pan, Margaret B. Allison, Paul Sabatini, Alan Rupp, Jessica Adams, Christa Patterson, Justin C. Jones, David P. Olson, Martin G. Myers, Jr.
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818312420

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http://www.sciencedirect.com/science/article/pii/S2212877818312420

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