Increased sarcolemmal Na+/H+ exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block

Increased sarcolemmal Na+/H+ exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block

Dogs with compensated biventricular hypertrophy due to chronic atrioventricular block (cAVB), are more susceptible to develop drug-induced Torsade-de-Pointes arrhythmias and sudden cardiac death. It has been suggested that the increased Na+ influx in hypertrophied cAVB ventricular myocytes contribut...

Full description

Bibliographic Details
Main Authors: Marcel evan Borren, Marc eVos, Marien eHoutman, Gudrun eAntoons, Jan Hindrik Ravesloot
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Physiology
Subjects:
NHE-1
NBC
AE
CHE
compensated cardiac hypertrophy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00322/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00322/full

Similar Items