Cerebral and peripheral changes occurring in nitric oxide (NO) synthesis in a rat model of sleeping sickness: identification of brain iNOS expressing cells.

BACKGROUND: The implication of nitric oxide (NO) in the development of human African trypanosomiasis (HAT) using an animal model, was examined. The manner by which the trypanocidal activity of NO is impaired in the periphery and in the brain of rats infected with Trypanosoma brucei brucei (T. b. bru...

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Bibliographic Details
Main Authors: Donia Amrouni, Sabine Gautier-Sauvigné, Anne Meiller, Philippe Vincendeau, Bernard Bouteille, Alain Buguet, Raymond Cespuglio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821905?pdf=render