Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis

Abstract Transient receptor potential canonical 5 (TRPC5), a calcium-permeable, non-selective cation channel is expressed in the periphery, but there is limited knowledge of its regulatory roles in vivo. Endogenous modulators of TRPC5 include a range of phospholipids that have an established role in...

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Bibliographic Details
Main Authors: Khadija M. Alawi, David Tandio, Jin Xu, Pratish Thakore, Georgia Papacleovoulou, Elizabeth S. Fernandes, Cristina Legido-Quigley, Catherine Williamson, Susan D. Brain
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02439-z