CD38 Deficiency Protects Heart from High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway

CD38 Deficiency Protects Heart from High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway

Background/Aims: Previous studies showed that CD38 deficiency protected heart from ischemia/reperfusion injury and high fat diet (HFD)-induced obesity in mice. However, the role of CD38 in HFD-induced heart injury remains unclear. In the present study, we have investigated the effects and mechanisms...

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Bibliographic Details
Main Authors: Ling-Fang Wang, Cong-Cong Huang, Yun-Fei Xiao, Xiao-Hui Guan, Xiao-Nv Wang, Qing Cao, Yu Liu, Xuan Huang, Li-Bin Deng, Ke-Yu Deng, Hong-Bo Xin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cd38
Oxidative stress
Heart Oleic acid
Sirt3/FOXO3 pathway
Online Access:https://www.karger.com/Article/FullText/492651

Internet

https://www.karger.com/Article/FullText/492651

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