Cloning and expression of <it>R-Spondin1 </it>in different vertebrates suggests a conserved role in ovarian development
<p>Abstract</p> <p>Background</p> <p>R-Spondin1 (Rspo1) is a novel regulator of the Wnt/β-catenin signalling pathway. Loss-of-function mutations in human <it>RSPO1 </it>cause testicular differentiation in 46, XX females, pointing to a role in ovarian develop...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-07-01
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| Series: | BMC Developmental Biology |
| Online Access: | http://www.biomedcentral.com/1471-213X/8/72 |