Significant elevation of free itraconazole concentration at onset of adverse effects: A case report

Abstract Free itraconazole and hydroxyitraconazole concentrations were markedly elevated despite almost no changes in total concentrations when itraconazole was discontinued due to adverse effects. Elevated free itraconazole concentration may have a causal relationship with the development of advers...

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Bibliographic Details
Main Authors: Ryota Tanaka, Yosuke Suzuki, Hiroyuki Matsumoto, Mari Yamasue, Kenji Umeki, Kazuhiko Hashinaga, Ryosuke Tatsuta, Kazufumi Hiramatsu, Katsuhiko Kamei, Jun‐ichi Kadota, Hiroki Itoh
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.3726