Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis

Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis

Non-alcoholic fatty liver disease affects approximately one billion adults worldwide. Non-alcoholic steatohepatitis (NASH) is a progressive disease and underlies the advancement to liver fibrosis, cirrhosis, and hepatocellular carcinoma, for which there are no FDA-approved drug therapies. We develop...

Full description

Bibliographic Details
Main Authors: Tracey Hurrell, Vlasia Kastrinou-Lampou, Achilleas Fardellas, Delilah F. G. Hendriks, Åsa Nordling, Inger Johansson, Audrey Baze, Céline Parmentier, Lysiane Richert, Magnus Ingelman-Sundberg
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
primary human hepatocytes
stellate cells
co-culture spheroids
COL1A1
CYP2E1
αSMA
Online Access:https://www.mdpi.com/2073-4409/9/4/964

Internet

https://www.mdpi.com/2073-4409/9/4/964

Similar Items