Formation and antiproliferative effect of prostaglandin E3 from eicosapentaenoic acid in human lung cancer cells
We investigated the formation and pharmacology of prostaglandin E3 (PGE3) derived from fish oil eicosapentaenoic acid (EPA) in human lung cancer A549 cells. Exposure of A549 cells to EPA resulted in the rapid formation and export of PGE3. The extracellular ratio of PGE3 to PGE2 increased from 0.08 i...
Main Authors: | Peiying Yang, Diana Chan, Edward Felix, Carrie Cartwright, David G. Menter, Timothy Madden, Russell D. Klein, Susan M. Fischer, Robert A. Newman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-06-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520318009 |
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