Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis.

Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis.

BACKGROUND:We previously reported that the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) down-regulates TLR4 signaling and lipopolysaccharide-induced apoptosis of hepatocytes. There have been several reports regarding the association between HCV infection and endoplasmic reticulum (ER) str...

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Bibliographic Details
Main Authors: Xia Jiang, Tatsuo Kanda, Shuang Wu, Shingo Nakamoto, Takaji Wakita, Hiroshi Shirasawa, Osamu Yokosuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4237446?pdf=render

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http://europepmc.org/articles/PMC4237446?pdf=render

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