Spironolactone and XPB: An Old Drug with a New Molecular Target

Spironolactone (SP) is commonly used for the treatment of heart failure, hypertension, and complications of cirrhosis by antagonizing the mineralocorticoid receptor. However, SP also antagonizes the androgen receptor, and thus SP has also been shown to be effective in the treatment of acne, hair los...

Full description

Bibliographic Details
Main Authors: Ryan D. Gabbard, Robert R. Hoopes, Michael G. Kemp
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/5/756