Compound C inhibits nonsense-mediated RNA decay independently of AMPK.

Compound C inhibits nonsense-mediated RNA decay independently of AMPK.

The nonsense mediated RNA decay (NMD) pathway safeguards the integrity of the transcriptome by targeting mRNAs with premature translation termination codons (PTCs) for degradation. It also regulates gene expression by degrading a large number of non-mutant RNAs (including mRNAs and noncoding RNAs) t...

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Bibliographic Details
Main Authors: Abigael Cheruiyot, Shan Li, Andrew Nickless, Robyn Roth, James A J Fitzpatrick, Zhongsheng You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6173407?pdf=render

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http://europepmc.org/articles/PMC6173407?pdf=render

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