Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner

Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner

Loop extrusion by structural maintenance of chromosomes (SMC) complexes has been proposed as a mechanism to organize chromatin in interphase and metaphase. However, the requirements for chromatin organization in these cell cycle phases are different, and it is unknown whether loop extrusion dynamics...

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Bibliographic Details
Main Authors: Stefan Golfier, Thomas Quail, Hiroshi Kimura, Jan Brugués
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
loop extrusion
SMC
cohesin
condensin
single molecule
cell cycle
Online Access:https://elifesciences.org/articles/53885

Internet

https://elifesciences.org/articles/53885

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