Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells.

Gene therapy continues to grow as an important area of research, primarily because of its potential in the treatment of disease. One significant area where there is a need for better understanding is in improving the efficiency of oligonucleotide delivery to the cell and indeed, following delivery,...

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Main Authors: Meesbah Jiwaji, Mairi E Sandison, Julien Reboud, Ross Stevenson, Rónán Daly, Gráinne Barkess, Karen Faulds, Walter Kolch, Duncan Graham, Mark A Girolami, Jonathan M Cooper, Andrew R Pitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057226?pdf=render