Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells.

We previously identified ovostatin 2 (OVOS2) as a new candidate gene for cutaneous malignant melanoma (CMM) in a Chinese population. In this study, we aimed to investigate the exact role of OVOS2 in cell proliferation, invasion, and tumorigenesis of melanoma A375 cells.The downregulation of OVOS2 ex...

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Bibliographic Details
Main Authors: Ying-Xue Huang, Hao Song, Yue Tao, Xue-Bao Shao, Xue-Si Zeng, Xiu-Lian Xu, Jin-Liang Qi, Jian-Fang Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5912766?pdf=render