E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding

E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding

Antagonistic interactions between transcription factors contribute to cell fate decisions made by multipotent hematopoietic progenitor cells. Concentration of the transcription factor PU.1 affects myeloid/lymphoid development with high levels of PU.1 directing myeloid cell fate acquisition at the ex...

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Bibliographic Details
Main Authors: Jason H. Rogers, Kristin S. Owens, Jeffrey Kurkewich, Nathan Klopfenstein, Sangeeta R. Iyer, M. Celeste Simon, Richard Dahl
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3983686

Internet

http://dx.doi.org/10.1155/2016/3983686

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