Whole genome sequencing, analyses of drug resistance-conferring mutations, and correlation with transmission of Mycobacterium tuberculosis carrying katG-S315T in Hanoi, Vietnam

Abstract Drug-resistant tuberculosis (TB) is a serious global problem, and pathogen factors involved in the transmission of isoniazid (INH)-resistant TB have not been fully investigated. We performed whole genome sequencing of 332 clinical Mycobacterium tuberculosis (Mtb) isolates collected from pat...

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Bibliographic Details
Main Authors: Nguyen Thi Le Hang, Minako Hijikata, Shinji Maeda, Pham Huu Thuong, Jun Ohashi, Hoang Van Huan, Nguyen Phuong Hoang, Akiko Miyabayashi, Vu Cao Cuong, Shintaro Seto, Nguyen Van Hung, Naoto Keicho
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-51812-7