Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus

Neuraminidase (NEU) is a key enzyme that cleaves negatively charged sialic acid residues from membrane proteins and lipids. Clinical and basic science studies have shown that an imbalance in NEU metabolism or changes in NEU activity due to various pathological conditions parallel with behavior and c...

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Bibliographic Details
Main Authors: Alina Savotchenko, Arthur Romanov, Dmytro Isaev, Oleksandr Maximyuk, Vadym Sydorenko, Gregory L. Holmes, Elena Isaeva
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/908190