A green process for the preparation of 11-{4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl}dibenzo[b,f][1,4]thiazepine

A green process for the preparation of 11-{4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl}dibenzo[b,f][1,4]thiazepine

A green process for the synthesis of 11-{4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl}dibenzo[b,f][1,4]thiazepine by the reaction of 11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine or its dihydrochloride salt with 2-(2-chloroethoxy)ethanol in the presence of an inorganic base and water is reported (conv...

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Bibliographic Details
Main Authors: GANESH D. MAHALE, ASHOK KUMAR, DHARMENDRA SINGH, SURESH B. WAGHMODE
Format: Article
Language:English
Published: Serbian Chemical Society 2008-04-01
Series:Journal of the Serbian Chemical Society
Subjects:
quetiapine
KI
tetrabutylammonium bromide (TBAB)
2-(2-chloroethoxy)ethanol
N
N-dimethylformamide
sodium carbonate
Online Access:http://www.shd.org.yu/JSCS/Vol73/No4/JSCS-3720.pdf

Internet

http://www.shd.org.yu/JSCS/Vol73/No4/JSCS-3720.pdf

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